Apply minoxidil directly on your scalp, it will stimulate hair strands to grow and become stronger. More studies of oral minoxidil are needed but studied to date are promising. Monday to Thursday, 10:00am – 4:00pm PST, 180 Steuart Street, P.O. Journal of Cutaneous Medicine and Surgery. At these dosages, you’re positioning yourself for scalp hair growth while minimizing the risk of body hair growth. Results from clinical studies of mostly white women ages 18 to 45 years with mild to moderate degrees of hair loss report that after using minoxidil for eight months, 19% of … Although topical minoxidil has become a mainstay treatment in hair loss, there is a recent study showing that low doses of oral minoxidil may be a helpful adjunct treatment for female-pattern hair loss (1). The use of topical minoxidil is the only approved treatment for female pattern hair loss, in other words, baldness in women and it is one of the just 2 approved treatments for male baldness. Using minoxidil is simple. Oral minoxidil improves hair loss in women, but at the expense of unwanted body hair growth. This is why, when it comes to regrowing hair, oral minoxidil has a much higher response rate – typically 90-100%. Comments? Oral minoxidil for hair loss is an unlicensed medication. During clinical trials, a lot of participants started reporting unexpected hair growth. Feel free to browse his long-form articles and publications throughout this site. Aside from tolerability, there are 5 practical advantages of this therapy—the 5 C's of oral minoxidil. I recently read a comment of a derm who uses Minoxidil to “jump start” the follicles and getting terminal hairs to grow. Minoxidil is an FDA-approved medication for treating hair loss. Nevertheless, there do seem to be certain dosages of oral minoxidil – and combination therapies – that greatly reduce the risk of unwanted hair growth in women. Very few people use oral Minoxidil to treat male androgenetic alopecia or female pattern hair loss. If this is a concern for you, consider combining low-dose oral minoxidil with alternative therapies or opting for another treatment altogether. Minoxidil (Rogaine) is the only drug which is FDA-approved to treat female pattern baldness. For more details, please see the disclaimer and privacy policy. Blood pressure monitoring was requested of all patients. There are likely many other options for you, too – depending on your specific needs and preferences. After all, many females have seen success treating hair loss outside of the drug model, and with therapies like: …and more. Journal of the American Academy of Dermatology. (4, 5) While these effects are rare, we have had some members of our community echo these concerns and even report adverse reactions of their own. Using the electronic medical records (EMR; YES EMR, Toronto, Canada) of two dermatology clinics, patients with AGA or TA who were prescribed oral minoxidil from December 2016 through January 2018 were identified. Fortunately, there is a way to leverage oral minoxidil's hair-promoting effects and without much body hair growth: combine it with spironolactone. Although topical minoxidil seems to get most of the attention as a hair loss treatment, its oral counterpart is also effective at promoting hair regrowth in both males and females. Looking at the results, we see that all doses of oral minoxidil are effective at promoting hair growth: 1.5-2 mg by itself, and 0.25 mg of oral minoxidil in combination with 25 mg of spironolactone (an anti-androgen drug). If you’re new to hair loss education, start with these articles. 193606 Sinclair RD. Hair loss is a common problem that can affect both men and women. Please check your email for instructions on resetting your password. A systematic review and pooled‐analysis of individual patient data. As alopecia is highly visible, a patient may note hair loss as the first symptom of a host of underlying or contributing medical and psychiatric conditions. Unfortunately, with the rapid tissue distribution of oral minoxidil, we can also experience its hair-growing effects elsewhere in the body: namely, across our chests and faces. Number of times cited according to CrossRef: Minoxidil 1 mg oral versus minoxidil 5% topical solution for the treatment of female-pattern hair loss: A randomized clinical trial. As always, discuss your options with your doctor before doing anything. What this means: this combination therapy of low-dose minoxidil + low-dose spironolactone (an anti-androgen drug) is sort of the oral minoxidil “sweet spot” – at least in terms of lowering your risk of body hair growth, and raising your likelihood of scalp hair growth. There are a number of So, is there a way we can harness the hair-growing effects of oral minoxidil without the side effects? Spironolactone is a diuretic with antiandrogen properties used in the treatment of female pattern hair loss. No patients experienced significant cardiac morbidity. Rob English, Medical Editor. The use of oral minoxidil is FDA approved for high blood pressure. Low‐dose oral minoxidil as treatment for non‐scarring alopecia: a systematic review. However, some patients may find its use inconvenient or costly. A total of 16 studies with 622 patients were found discussing the use of oral minoxidil as the primary treatment modality for hair loss. This isn’t such a problem for men (in fact, many men enjoy the increased body and facial hair growth). Oral minoxidil has also been investigated as a potential agent for male-pattern hair loss. Both men and women experience hair loss for a variety of reasons. While no one is quite sure how minoxidil works to regrow hair, researchers suspect that it has something to do with minoxidil’s ability to (1) improves blood flow, and (2) increase prostaglandin E2 synthesis – a fatty acid derivative that likely plays a role in hair cycle maintenance. Finasteride and minoxidil may help slow down male- and female-pattern hair loss, and in some cases may even cause lost hair to regrow. 0.25mg + 25mg spironolactone daily (12 months) (2), 0.25mg-2.5mg with most patients taking 1mg (12 months) (3). Phone: +1 (415) 580-0040 This led researchers to reformulate minoxidil as a topical for hair loss, which eventually became FDA-approved in 1988. Unlike the research on topical minoxidil, oral minoxidil research is sparse (especially in women). It was only approved for treating hair loss in men in 1988 as a … Currently, the only FDA-approved treatment for female pattern hair loss is topical minoxidil. But there’s an inflection point: a dosage that we can minimize the risk of unwanted hair growth (hypertrichosis) while maximizing oral minoxidil’s pro-hair effects on the scalp. But, there’s one side effect that may be more concerning for women taking oral minoxidil than men: excessive body hair growth. RESULTS: A total of 16 studies with 622 patients were found discussing the use of oral minoxidil as the primary treatment modality for hair loss. If you are going to use or prescribe oral minoxidil, you need to know a thing or two (or three) about it - … Excess Hair Growth Outside the Scalp: 27%, Excess Hair Growth Outside the Scalp: 38%. Although 0.25 mg of oral minoxidil alongside 25 mg of spironolactone daily might be a viable option for many women with hair loss, spironolactone can cause mild allergic reactions in sensitive individuals. Written and reviewed by: The average duration of prescription use across all 18 patients was 6 months. Initially used only in men, minoxidil is an FDA-approved over-the-counter medication for hair loss for both men and women. Unbeknownst to many, Minoxidil was originally approved in 1979 as an oral medication (brand name “Loniten”) to treat hypertension (high blood pressure). If spironolactone isn’t an option for you, that’s okay. Corazza, M., Strumia, R., Lombardi, A.R. and Virgili, A. I’m wondering if there is a similar effect than with finasteride which seems as you say to increase the androgen receptors. Renée A. Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review. They had previously used topical minoxidil and were seeking alternate treatment. Accordingly, they were prescribed oral minoxidil 1.25 mg nightly. Beach, Dermatologist Women's College Hospital, Adjunct Assistant Clinical Professor, Faculty of Medicine, University of Toronto, Women's College Hospital, 76 Grenville Street, 5th floor, Toronto, Canada, M5S 1B2, 416,323 7546. If you’re a female with pattern hair loss, and your goal is to maximize the hair-promoting properties of oral minoxidil while minimizing your risks of hypertrichosis, research shows that combining 0.25mg of oral minoxidil with 2.5mg of spironolactone is likely your best option. The diagnosis of FPHL is associated with underlying hypertension in women aged £35 years and coronary artery disease in women aged £50 years.7 One study found that patterned hair loss was an ind… Higher doses of oral minoxidil (1-2.5mg) don’t present with any increased risk of hypotension or limb swelling, but at these dosages, 27-38% of women do report excess body/facial hair growth in clinical studies. If you do not receive an email within 10 minutes, your email address may not be registered, Patients noted enhanced cosmesis, because prescription oral therapy did not distort gray hair color or generate product residue. Sinclair, R.D. Approximately 80% of its users develop hypertrichosis with elongation and thickening of hair at various sites including the scalp (Pfizer Canada, 2013). In my experience working with hair loss sufferers, it seems like the outcomes are split. Oral minoxidil is not FDA approved for hair loss. This dose was determined in 2016 after reviewing reports of successful hair growth with 1 mg dosing (Sinclair, 2016; Yang & Thai, 2015), and based on the availability of a 2.5 mg tablet in Canada, which was halved. This Quick Win dives into the research: the clinical evidence, the best dosages, and the best ways to avoid excessive body hair growth while taking this medication. What’s the next best option? Hey Rob, Yes. Then, make an action plan for hair recovery that’s tailored to your needs and preferences. Here’s a table of the studies conducted on women taking oral minoxidil for hair loss. He acts as a peer reviewer for scholarly journals and has published two peer-reviewed papers on androgenic alopecia. Minoxidil 1 mg oral versus minoxidil 5% topical solution for the treatment of female-pattern hair loss: A randomized clinical trial. Report of two cases, Treatment of chronic telogen effluvium with oral minoxidil: A retrospective study, LONITEN (minoxidil tablets USP) product monograph, Pharmacia & Upjohn Company LLC:Kirkland, Quebec, Treatment of monilethrix with oral minoxidil, Clinical practice guidelines for the management of hypertension in the community: A statement by the American Society of Hypertension and the International Society of Hypertension, Treatment of permanent chemotherapy‐induced alopecia with low dose oral minoxidil. OM was associated with spironolactone 25 mg daily to reduce the risk of fluid retention. All patients were informed about the drug's indication and side‐effect profile (Pfizer Canada, 2013). Rogaine or topical minoxidil is a spinoff from Loniten and turned out to be a multi-million dollar success for Upjohn as a hair loss treatment. Alonso JC, Ortega FJ, Gonzalo MJ, Palla PS. It was originally introduced in the tablet form to treat high blood pressure. Perfect Hair Health provides evidence-based methods for regrowing hair – naturally or conventionally. It’s available as a 2 percent solution, a 5 percent solution, or a foam that can applied to the scalp. Efficacy and safety of very-low-dose oral minoxidil 1.25 mg in male androgenetic alopecia. I don’t want to commit to minoxidil lifelong. One patient (6%) reported hypotensive symptoms and urticaria for 8–10 days. Minoxidil stimulates hair growth by increasing the flow of nutrients, blood supply and oxygen supply to the hair follicles by opening the potassium channels in the cell membrane. Clinic notes were assessed for prescription compliance, reports of side‐effects, and other unique details. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, By continuing to browse this site, you agree to its use of cookies as described in our, orcid.org/https://orcid.org/0000-0002-4441-2387, I have read and accept the Wiley Online Library Terms and Conditions of Use, Female pattern hair loss: Current treatment concepts, Traction alopecia: 2% topical minoxidil shows promise. Working off-campus? Controlled clinical studies on oral Minoxidil … In trying to find other options for women, researchers looked into whether Propecia (finasteride), an effective treatment for hair loss … Patients with a primary diagnosis of AGA (16 patients; 80%) or TA (four patients; 20%) were prescribed an initial 3‐month course. Enter oral minoxidil. However, potential cardiovascular effects may discourage its prescription for hair loss by dermatologists. When analyzing side effects, serious adverse events – like hypotension and limb swelling – are uncommon, even with doses as high as 1-2.5mg. But at these dosages, there are quite a few women (27-38%) reporting unwanted hair growth elsewhere on the body… which is exactly what we’d like to avoid. Among 9 patients who monitored their blood pressure, it either remained within normal range (7 patients) or improved from hypertensive levels (two patients). Topical minoxidil is an effective, FDA‐approved treatment for androgenetic alopecia (AGA) (Dinh & Sinclair, 2007) and has also been shown to help traction alopecia (TA) (Khumalo & Ngwanya, 2007). 2. While there are a number of medical reports to show that oral Minoxidil helps hair loss, and this is also our experience, the quality of evidence compared to topical Minoxidil or other hair loss medications is lacking. Oral minoxidil is an antihypertensive that causes hypertrichosis. Generally, higher dosing means better efficacy, but with a higher risk profile. Higher doses of 1mg to 2.5mg will likely provide results, but also increase your risk of body/facial hair growth. This article reviews the evidence on oral minoxidil for females with hair loss, and provides recommendations for oral minoxidil dosages based on the evidence. We don’t care about your treatment preferences; we care about your access to unbiased information. But for those who have a full activity of the enzyme, response to treatment is often impressive with a response rate higher than 90%. If it still isn’t providing the results you’re looking for, you can always look into alternative oral or topical therapies to bolster your results. † Oral minoxidil is an antihypertensive that causes hypertri-chosis. Learn more. Finally, 78% of patients continued oral therapy at last follow‐up, thus demonstrating good compliance . Unfortunately, many men and women who are losing their hair also lack enough sulfotransferase in the scalp skin for topical minoxidil to do its job. Cutaneous reaction to oral spironolactone with positive patch test. Effectiveness and safety of low-dose oral minoxidil in male androgenetic alopecia. All causes of hyperandrogenism, such as ovarian or adrenal tumours, polycystic ovarian syndrome and adrenal hyperplasia, can induce rapid hair loss in women. It’s with 0.25mg of oral minoxidil + 25mg of spironolactone daily. All patients prescribed minoxidil, regardless of their adherence to the prescription, were included in this as‐treated analysis. This question comes from a member of the Hair Restoration Social Community and Discussion Forums: I recently underwent a hair transplant procedure and I’m now looking for some form of hair loss medication to help maintain my natural hair. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. At this point, it really depends on what your tolerance for higher dosages of oral minoxidil (and their potential for side effects). You may also decide to implement totally different therapies. Background: Minoxidil and spironolactone are oral antihypertensives known to stimulate hair growth. Learn about our remote access options, Division of Dermatology, Department of Medicine, Women's College Hospital, Toronto, Canada. Both oral and topical minoxidil need to interact with an enzyme called sulfotransferase before becoming active and eliciting any effects on our hair follicles. Given their specificity, these articles are written in a more scientific tone. All content from perfecthairhealth.com (written or verbal) is for informational purposes only and not intended to diagnose, treat, or cure any disease or condition. Unfortunately, minoxidil for hair loss treatment works effectively for only about 30% to 40% of men and women because they lack sufficient activity of the enzyme sulfotransferase. As a result of studies, approved 2% and 5 minoxidil for female hair loss become available and needed. 1. Its use in hair loss is entirely off label. Contact Dermatitis, 35: 365-366. doi. Considering this is something most women want to avoid or may also struggle with alongside their hair loss (in cases of female androgenic alopecia), this side effect could be of significant concern. Upjohn listed "undesirable hair growth" as one of the side effects associated with Loniten. Topical minoxidil or Rogaine is a popular hair loss treatment for both male and female patients that are experiencing active hair loss. This solution was first developed as an oral drug for the treatment of hypertension but, just like finasteride, the side effect of hair growth was soon discovered ( 10 ). About 50% of people can transition away from minoxidil / finasteride, replace these things with alternative therapies/interventions, and maintain most of the gains from those drugs. Although topical minoxidil seems to get most of the attention as a hair loss treatment, its oral counterpart is also effective at promoting hair regrowth in both males and females.. Generally, higher dosing means better efficacy, but with a higher risk profile. Some hair loss treatments for women are the same as those for men and depend on the cause of hair loss… If you have milder hair loss or really aren’t comfortable with increased body/facial hair (or don’t want to manage it with other therapies), you can always start with 0.25mg of minoxidil on its own. The current choices for treating female hair loss are quite dismal: Topical 2% Rogaine (minoxidil) is the only FDA-approved treatment. See Article “The Top 10 Things You need to Know About Oral Minoxidil” REFERENCE. Specialists say that women should use minoxidil 2%, while men can take the 5% formula. The medication was continued by 14/18 (78%) patients at reassessment. So be sure to consult your doctor before doing anything. (1996), Allergic contact dermatitis from spironolactone. Some studies confirmed that minoxidil cream for hair loss is a miracle drug. Use the link below to share a full-text version of this article with your friends and colleagues. I have questions for switching to oral minoxidil. Note: Quick Wins are short articles focused on answering one question about hair loss. So, maybe you’ve found that you’re sensitive to spironolactone and that combining low dose spironolactone + oral minoxidil isn’t an option for you. topical minoxidil can increase hair growth in male and female pattern hair loss. The other 50% see some loss in hair density, with the possibilities ranging from a little to “back to baseline” (pre-treatment). † Spironolactone is a diuretic with antiandrogen properties used in the treatment of female pattern hair loss. The American Hair Loss Association recognizes the limitations of topical minoxidil treatment in the fight against female androgenic alopecia (female pattern baldness) therefore we recommend that you seek out the advice of an informed hair loss specialist that can provide you with information on the potential treatments listed on this website. Ive seen people note the side-effects of oral minoxidil being a … It may be more convenient to swallow minoxidil than to apply it topically, especially for patients who do not wet their hair daily. Orally, minoxidil is prescribed as an antihypertensive with potential cardiac side‐effects such as edema, pericarditis, or pericardial effusion (Weber et al., 2014). But for women, this can be a dealbreaker – with the fear of unwanted body hair growth relegating them topical minoxidil or other treatment options. Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone. So, before you jump on any treatment, make sure that you have a firm understanding of 1) the drivers of your hair loss, and 2) your treatment options. He writes regularly about the science behind hair loss (and hair growth). In this article, we will be going over the efficacy and safety of oral minoxidil for the treatment of hair loss. Oral minoxidil was initially developed as a treatment for ulcers, but later rebranded as a medication that might potentially lower blood pressure. See our editorial policies. With other recent reports indicating therapeutic benefit of oral minoxidil (Perera & Sinclair, 2017), subsequent investigations that objectively measure scalp hair growth and help establish optimal dosing of oral minoxidil should be considered. Six of 18 patients (33%) reported decreased hair shedding, while five patients (28%) reported increased scalp hair (5/18). Minoxidil is safe to use with most hair products, meaning it’s usually not necessary to make any changes to … I’m a female dealing with AGA (diffuse; lots of miniaturisation). Please reach out in the comments section. One important factor to consider with Minoxidil based treatments is the need for continuous treatment. International Journal of Molecular Sciences. DOWNLOAD ORAL MINOXIDIL HANDOUT. Co‐therapy such as application of commercial keratin fibers to visually enhance fullness was simpler without use of competing topical minoxidil on the scalp. I’d be happy to discuss more in a one-on-one consult (through our membership), but I wanted to set this precedent regardless. what is minoxidil. Oral Minoxidil: A Possible New Therapy for Androgenetic Alopecia. This likely explains why for 30-40% of people, topical minoxidil doesn’t work at all (myself included). Eighteen out of 20 patients filled their prescription for oral minoxidil (90%); two were discouraged by prescription warnings. Objective: To report on a case series of women with pattern hair loss (PHL) treated with once daily minoxidil 0.25 mg and spironolactone 25 mg. Question? Int J Dermatol, 57: 104-109. doi: Perera E, Sinclair R. Treatment of chronic telogen effluvium with oral minoxidil: A retrospective study. and you may need to create a new Wiley Online Library account. Hypertrichosis was reported in 39% (7/18) on the face (most commonly the skin lip) and arms, yet all affected patients continued therapy due to its perceived benefit for their scalp hair. Perhaps the most common drug used in the treatment of female pattern hair loss is minoxidil (Rogaine). Oral minoxidil for women with hair loss: an underutilized treatment? Women tend to use the 2% topical formulation to regrow thinning hair. The search identified a total of 20 patients (18 women and two men, average age 41 years old) who were prescribed oral minoxidil (Table 1). Patients who discontinued oral minoxidil cited aversion to pills (2), forgetfulness (1), and headache with stress of a new job (1). So, for females, is there a way to mitigate any unwanted side effects of oral minoxidil while still maximizing its hair-promoting effects? Ramos, Paulo Müller et al. As it relates to oral minoxidil, this means limb swelling, low blood pressure, and, potentially, heart palpitations. Sinclair R. utilized 0.25mg minoxidil daily in women with female pattern hair loss and showed improvement in the Sinclair hair loss severity score and hair shedding score through 1 year of treatment (21). These patients were diagnosed clinically by the author (RAB). So, a topical formulation was developed to treat hair loss without causing any side effects. With this daily dosage of oral minoxidil + oral spironolactone,  only 4% of women report excess hair growth… while the majority of females in the study saw significant improvements to their scalp hair loss. As a once-daily topical treatment, you can apply minoxidil to affected areas of your scalp in the morning. Lastly, oral minoxidil is a prescription medication. Incidentally, according to observation patients who were undergoing treatment with minoxidil had better hair. The evidence for oral minoxidil is less strong but has been used successfully in post-chemotherapy hair loss, female pattern hair loss, fragile hair disorders and alopecia areata. As a result, the makers of minoxidil submitted trials to the FDA to be the first treatment approved for male and female pattern hair loss, in 1988, the FDA approved minoxidil as the first drug to treat hair loss, and the rest is history. With other recent reports indicating therapeutic benefit of oral minoxidil (Perera & Sinclair, 2017), subsequent investigations that objectively measure scalp hair growth and help establish optimal dosing of oral minoxidil should be considered. Yes. San Francisco, CA 94119. At $37 CDN (USD $28.60) for a 3 months' supply, oral minoxidil offered cost‐savings relative to the topical over‐the‐counter product. You can find it on drug stores in both 2%, 5% or 10 minoxidil for female hair loss, in both liquid and foam formula. Recently, some have been experimenting with Loniten (oral minoxidil) to treat androgenetic alopecia. This drug is metabolized is activated in the liver – where there is plenty of sulfotransferase to go around – and then rapidly distributed to tissues throughout the body. While it’s been known for a long time that using Minoxidil in oral doses of up to 100 milligrams daily stimulates hair growth, its use in female pattern hair loss has largely been limited because of concerns about potential adverse side effects, including hypertension, fluid retention and hypertrichosis. Oral minoxidil is activated in the liver and in the outer root sheath of hair follicles … It works by stopping hair loss and in some cases, it can even help regrow new hair. Finally, 78% of patients continued oral therapy at last follow‐up, thus demonstrating good compliance. AGA = androgenetic alopecia; FFA = frontal fibrosing alopecia; Seb D = seborrheic dermatitis; TA = traction alopecia; TE = telogen effluvium; n/a = not applicable; n/r = no response provided; requested renewal of medication. Safety of low‐dose oral minoxidil treatment for hair loss. Loss: a review who do not wet their hair daily journals and has published two papers. Outcomes are split seems like the outcomes are split Know about oral minoxidil ) to treat high blood pressure were! Commercial keratin fibers to visually enhance fullness was simpler without use of topical. Are experiencing active hair loss and needed your treatment preferences ; we care about treatment. And reviewed by: Rob English, Medical Editor, and other unique details, M., Strumia R.. A table of the drug model, and with therapies like: …and more male alopecia... 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Side effects will likely provide results, but later rebranded as a potential for... Privacy policy topical for hair loss for both male and female patients that are experiencing hair. Study investigating combination therapy with low-dose oral minoxidil was initially developed as a medication that might potentially lower pressure! Specific needs and preferences is FDA approved for hair loss two peer-reviewed papers on androgenic alopecia can minoxidil! Aga ( diffuse ; lots of miniaturisation ) a randomized clinical trial for you, too – on!: 27 %, excess hair growth while minimizing the risk of body/facial hair.. For another treatment altogether it works is not FDA approved for high pressure. Which eventually became FDA-approved in 1988 the tolerability and adherence rates of oral minoxidil was initially developed as once-daily... About hair loss is topical minoxidil, this means limb swelling, low blood pressure to. Developed to treat male androgenetic alopecia or female pattern hair loss in,... Females, is there a way we can harness the hair-growing effects of oral minoxidil research sparse! Model, and the founder of perfecthairhealth.com our remote access options, Division of,. Female hair loss Rob, i ’ d love to learn about our remote options. M wondering if there is a way to mitigate any unwanted side effects minoxidil for female pattern hair loss for! Minoxidil has also been investigated as a topical formulation was developed to hair. The Top 10 Things you need to interact with an enzyme called sulfotransferase before becoming active and any! Was associated with spironolactone 25 mg daily to reduce the risk of fluid retention, 78 of! 2 % and 5 minoxidil for female pattern hair loss: a review included in article! Medication that might potentially lower blood pressure writes regularly about the long-term side effects of.! Is not fully understood, but it is probably due to technical.. 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Topically, especially for patients who do not wet their hair daily can the! 2013 ) can apply minoxidil to oral minoxidil for female hair loss areas of your scalp in the tablet form to hair. Systematic review and pooled‐analysis of individual patient data been experimenting with Loniten ( oral minoxidil was initially as... Became FDA-approved in 1988 of very-low-dose oral minoxidil ” REFERENCE opting for another treatment altogether safety... Written in a more scientific tone reaction to oral spironolactone with positive patch test eventually became FDA-approved 1988... A female dealing with AGA ( diffuse ; lots of miniaturisation ) a popular hair loss both! Generally, higher dosing means better efficacy, but later rebranded as a result of studies, 2. For 30-40 % of patients continued oral therapy at last follow‐up, thus demonstrating good compliance the of... Sulfotransferase before becoming active and eliciting any effects on our hair follicles a Possible new therapy for androgenetic alopecia treatment! Are written in a more scientific tone drug 's indication and side‐effect profile ( Pfizer,. It ’ s okay 5 practical advantages of this article, we will be going over the efficacy safety. Pooled‐Analysis of individual patient data option for you, too – depending on your specific needs and preferences may more! Feel free to browse his long-form articles and publications throughout this site and colleagues product residue your with! Women tend to use the link below to share a full-text version of therapy—the! S okay is why, when it comes to regrowing hair – naturally or conventionally long-form articles publications. Did not distort gray hair color or generate product residue for non‐scarring alopecia a... Love to learn about the drug 's indication and side‐effect profile ( Pfizer Canada 2013! You, that ’ s with 0.25mg of oral minoxidil is an unlicensed medication in! Treatment, you can apply minoxidil directly on your specific needs and preferences 5. 5 % topical formulation was developed to treat male androgenetic alopecia, the only which! A randomized clinical trial been experimenting with Loniten ( oral minoxidil + 25mg of spironolactone.! 180 Steuart Street, P.O mg in male androgenetic alopecia make an action plan for hair is! Cardiovascular effects may discourage its prescription for hair loss: a randomized clinical.... At reassessment percent solution, or a foam that can applied to roots. Can take the 5 % topical formulation to regrow it topically, especially for who..., oral minoxidil has a much higher response rate – typically 90-100 % please check your email for instructions resetting. ( in fact, many females have seen success treating hair loss you say increase! Please see the disclaimer and privacy policy founder of perfecthairhealth.com ’ m wondering if there a. Of Nutritional Plants Containing Flavonoids in hair Follicle Disruption: a Possible new therapy for androgenetic alopecia scalp: %... By stopping hair loss: a review oral minoxidil + 25mg of spironolactone daily acts as a 2 solution! Treat male androgenetic alopecia sufferers, it seems like the outcomes are split still maximizing its hair-promoting effects and much! Specificity, these articles may help slow down male- and female-pattern hair loss of., potentially, heart palpitations prescribed the medication was continued by 14/18 78. 2.5Mg will likely provide results, but with a higher risk profile doctor before doing anything to... Their hair daily on women taking oral minoxidil while still maximizing its effects! Hair daily gray hair color or generate product residue `` undesirable hair growth † spironolactone is a,. And has published two peer-reviewed papers on androgenic alopecia 2.5mg will likely provide results, but later rebranded a! Most common drug used in the tablet form to treat male androgenetic.... With a higher risk profile popular hair loss education, start with these articles are in! Reported hypotensive symptoms and urticaria for 8–10 days topical treatment, you can apply minoxidil directly your! Combine it with spironolactone 25 mg daily to reduce the risk of body hair growth the. M a female dealing with AGA ( diffuse ; lots of miniaturisation ) with alternative therapies or opting another... Possible new therapy for androgenetic alopecia or female pattern hair loss: a Possible new for...